Research Associate Mucosal Immunology

University of Cambridge - Department of Medicine

Cambridge, United Kingdom

The human gastrointestinal tract houses a large number of microbes, collectively known as the microbiota, that supports host metabolism, immune development and pathogen resistance. The Pedicord Lab at the University of Cambridge Department of Medicine seeks to gain mechanistic insights into the influence of the microbiota on local and systemic immune responses. These insights will enable the development of new approaches to combat intestinal infections and inflammation and augment cancer immunotherapy.

Applications are invited for a Postdoctoral Research Associate to work with Dr Virginia Pedicord at the Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID) in the Jeffrey Cheah Biomedical Centre to explore the mechanisms by which commensal microbes affect disease susceptibility. This will involve using in vivo models, cellular immunology, transcriptomics and proteomics to characterise the complex interactions between the intestinal epithelium, immune cells and commensal microbial community. The ideal applicant will love scientific investigation, have a good work ethic and excellent organisation skills, be detail-oriented, persistent, and passionate about working as a team to build a successful research group. Applicants must have a PhD degree in Biological Science with a focus on Microbiology or Immunology, preferably with some experience in murine in vivo infection and/or inflammation models. Experience with proteomics, transcriptomics, advanced imaging and/or bioinformatics strongly preferred but not required.

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