Post-doctoral Position - Role of F3 Tissue Factor in Astrocyte Function
The Lab of Glia Biology is looking for a skilled post-doctoral scientist to join the team by early - mid 2017.
F3 (or tissue factor) is a protein widely known for its role in blood coagulation. However, in the central nervous system (CNS), F3 is most heavily expressed in astrocytes. Astrocytes are a major cell type of the CNS - and play a number of important roles ranging from synapse formation and modulation of synaptic transmission, through to involvement in blood brain barrier formation and control of cerebral blood flow.
Under normal circumstances, astrocytes should not come into contact with blood. Therefore, this project aims to understand the role of F3 in the CNS – and the underlying molecular pathways responsible for its function.
With access to a wide range of state-of-the-art techniques (such as quantitative mass-spectrometry through to in vivo imaging), this project provides an outstanding opportunity for an ambitious post-doc to establish a novel independent research line in the emerging field of astrocyte research.
- Candidates must have, or expect to obtain, a Ph.D. degree and be highly trained in molecular biology and biochemistry techniques.
- A strong track record, as shown through multiple contributions to the scientific literature, is essential.
- Experience in mouse husbandry and use of the Cre-Lox system is desirable.