Postdoctoral Position, Ion Beam and Synchrotron Radiation Imaging of Uranium Distribution in Neurons
CENBG - CNRS - University of Bordeaux
- The aim of this project is to provide insight into the risk thresholds and disturbance mechanisms induced by low concentrations of natural uranium on a neural cell model;
- The rate of intracellular accumulation of uranium, its distribution in cell organelles, its impact on the homeostasis of endogenous essential trace metals, will be determined by means of ion beam and synchrotron radiation imaging techniques.
- The candidate will focus on the acquisition and processing of data on the high spatial resolution ion beam line of the CENBG particle accelerator using PIXE (Particle Induced X-ray Emission) and RBS (Rutherford Backscattering Spectrometry), as well as experiments on synchrotron XRF (X-Ray Fluorescence) microscopy facilities;
- The candidate will prepare the biological samples according to the appropriate cryogenic methods;
- The candidate will use and develop software tools for correlative imaging (ImageJ);
- The candidate will supervise Master students.
- PhD in Experimental Physics or Analytical Chemistry with advanced knowledge of chemical imaging techniques using ion beams or synchrotron radiation;
- Experience in biological applications will be an important asset;
- Demonstrated experience in publishing research results;
- Required qualities: team spirit, pedagogical qualities, open-mindedness, interdisciplinary general knowledge.
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