Post-doctoral Position for a Molecular Parasitologist/Systems Biologist
The post-doctoral fellow will be establishing the single-cell protocols (based on FACS sorting and/or single cell technologies) for transcriptomic analyses of individual sporozoites. Initially these protocols will be developed using sporozoites from culturable parasites available at Institute Pasteur (i.e. P. falciparum and/or P. berghei). Once established, an in-depth single cell analysis of sporozoites of the relapsing monkey parasite P. cynomolgi will be undertaken. Lastly, working with researchers based in Pasteur Institute International Network Institute based in P. vivax endemic countries (e.g. Cambodia, Madagascar and/or French Guyana), we will establish systems for producing sporozoites using standard membrane feeding assay and conduct single-cell analyses of sporozoites from areas with differing P. vivax relapse phenotypes. In addition, the postdoc will be responsible for supervising the work done by our technicians in our high-throughput molecular and sero-epidemiology laboratory.
The position will require a high degree of self-motivation and ability to work independently as well as a willingness to collaborate closely with colleagues at the Walter + Eliza Hall Institute in Melbourne, Australia and with endemic country scientist (including spend time working in the endemic countries and mentor of PhD and MSc students).
Candidates should possess a PhD in molecular parasitology or systems biology with a solid knowledge of genome and/or transcriptome analyses (DNA/RNAseq and bioinformatics analyses). Experience in single cell and high-throughput approaches would be beneficial but not a requirement.