The Neurovascular Diseases Research Group (PI: Gabor Petzold) is interested in the pathogenesis of stroke, vascular dementia and neurodegenerative diseases, with a particular focus on glial cells and vascular factors contributing to cognitive decline. We use techniques such as in vivo two-photon microscopy, ischemia models, electrophysiology, whole-brain clearing techniques, small-animal MRI, and behavioral assessment. We possess, or have unlimited access to, state-of-the-art equipment and facilities.
For this position funded by the German Research Foundation (DFG), we aim to investigate the role of astroglial and neuronal glutamate homoeostasis in animal models of stroke, based on our previous work (e.g. J Clin Invest 2017). Techniques used in this project will include in vivo calcium and glutamate imaging using genetically engineered fluorescent indicators, focal ischemia, transgenic manipulation, chronic drug administration and behavioral assessment.
We are looking for a highly motivated individual with a PhD, MD or MD/PhD degree to join our group as a postdoctoral researcher for three years. The applicant should ideally have a good track record and/or strong expertise in mouse stroke models (including surgery and anesthesia) and in vivo imaging. Fluency in English, excellent communication skills, and the ability to work in a multicultural international environment are also required.