Bioinformatician

Bioinformatician

EMBL-EBI - European Bioinformatics Institute

Hinxton, United Kingdom

An exciting opportunity has been created for a talented bioinformatician to work on methods for the annotation of drug discovery relevant data. The position is funded by the Open Targets initiative which is a public-private initiative between EMBL-EBI, GlaxoSmithKline, Biogen, Takeda, Celgene, Sanofi and the Sanger Institute to generate and integrate evidence on the validity of biological targets for drug development.

Based in the ChEMBL Team at the European Bioinformatics Institute (EMBL-EBI) the appointee will work with the Open Targets partners to develop pipelines for the identification and integration of information and data to support the role(s) of biological targets in disease into the Open Targets Platform

Your role

Reporting to the ChEMBL team leader, you will have excellent attention to detail, strong communication skills and be able to interact with technical experts as well as scientists seeking solutions to their "real world" problems. The specific job responsibilities include:

  • To extend and validate pipelines for identifying target to drug to disease links by utilising a variety of resources such as ChEMBL, clinical trials data, the scientific literature and patents;
  • Curate the potential therapeutic targets of drug molecules and compounds in clinical development from a variety of sources such as the scientific literature, Pharma Company pipelines and prescribing information;
  • Carry out mapping of disease terms to existing public ontologies;
  • Develop a text mining pipeline to identify and extract clinical trials outcomes from public data sources;
  • Work with the Open Targets partners to assess, validate and refine the resulting methods;
  • To work with Open Targets core team to integrate the data into the Open Targets Platform.

You have

  • A PhD (or equivalent) in a biological or biomedical science;
  • Sound knowledge of disease biology and the mechanisms of drug action;
  • Proficiency in at least one programming/scripting language (e.g. Python, Perl etc.);
  • Experience in data handling, manipulating file formats and working with ontologies;
  • Ability to work accurately and quickly to deadlines;
  • Able to work both as part of a team and independentl;
  • Good communication skills (both verbal and presentational).

You might also have

  • Experience of biological data curation and knowledge of bioinformatics databases
  • Experience working with clinical trials or drug candidate data
  • Experience working in a drug discovery and development environment.

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© EuroJobsites 2019

EuroJobsites is a UK registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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