Postdoctoral Researcher in Structural Biology for the Study of Redox Sensitive Proteins

Postdoctoral Researcher in Structural Biology for the Study of Redox Sensitive Proteins

VIB

Brussels, Belgium

Position

A postdoctoral research position is immediately available for structure-function studies of proteins involved in redox metabolite signaling. Successful candidates will join the exciting research environment of the Messens laboratory at the VIB-VUB Center for Structural Biology in Brussels, Belgium.

The Messens laboratory is recognized as a world leader in the redox field, and the lab provides an outstanding position in protein biochemistry and structural biology, in a highly dynamic and team-oriented research group. In this cutting-edge research environment, you will tackle essential biological problems in metabolite signaling.

Mission of the Lab

We decipher how cells sense redox metabolites and transduce stimuli into downstream biological effects. Knowledge of the mechanisms by which sensors and transducers function are invaluable in understanding how redox homeostasis pathways can be engineered with the ultimate goal of improving oxidative stress resistance in plants and to identifying therapeutic targets in diseases such as diabetes and cancer, which have been associated with aberrant redox signaling.

Your role in the lab

You will be involved in a project that exploits prokaryotic proteins for the de novo design of biosensors with a fluorescent read-out for both in vitro studies and live imaging of cellular metabolic changes. Further, your expertise will be needed for the structural and functional analysis of plant H2O2-sensing proteins to understand how organelle communication functions at the molecular level.

Requirements

  • Applicants should have obtained a PhD in the last 5 years within the field of structural protein biochemistry and should have thorough hands-on expertise with protein purification, protein crystallization, data collection at synchrotron beamlines, and solving protein structures.
  • Fluency in English is a must.
  • Experience with biophysical techniques is a plus, but not required.

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© EuroJobsites 2019

EuroJobsites is a UK registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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