Postdoctoral Researcher in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Research

Postdoctoral Researcher in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Research

DZNE - German Centre for Neurodegenerative Diseases

Tübingen, Germany

The main goal of the research group “Molecular Neuropathology of Neurodegenerative Diseases” (Prof. Dr. Manuela Neumann) is to understand the molecular mechanisms underlying frontotemporal dementia and amyotrophic lateral sclerosis, with specific emphasis on the role of TDP-43, FET proteins and C9orf72 in the pathogenesis.

Your tasks

The specific focus of the project will be on the identification of posttranslational modifications of TDP-43 and FET proteins and characterization of their functional consequences with respect to the normal function of these proteins and their role in the disease pathogenesis. Identified modifications will also be tested for suitability as biomarker and drug target. Primary methods will include different protein purification methods, biochemical separation techniques, mass spectrometry and cell culture.

Requirements

Applicants must have a Ph.D. and should have a strong background in protein biochemistry and molecular biology. Prior experiences in protein research and biochemical analytics are highly desirable. Applicants should be fluent in English and possess good communication and team working skills.

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© EuroJobsites 2019

EuroJobsites is a UK registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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