Postdoc Population Genetics in Rheumatology

Postdoc Population Genetics in Rheumatology

Leiden University Medical Center

Leiden, Netherlands

We are looking for an ambitious and enthusiastic postdoctoral researcher with strong background in genetic epidemiology to expand our team. As part of the large EU consortium, you will be working in close collaboration with data scientists, epidemiologists, statisticians and doctors within Europe (including England, Sweden, Germany, Spain, Hungary and Greece). Do you have a strong background and interest in epidemiology and population genetics and are motivated to expand your skills further in such a unique translational set up? Then you could become our new colleague!

About your role

As a postdoc in our group, you will play a pivotal role in conducting and coordinating genetic analyses. Your primary responsibility will be to establish an analytical framework for studying and identifying novel genetic predispositions related to rheumatic diseases. This framework will be instrumental in optimizing disease stratification among individuals with rheumatic complaints. Our goal is to deepen our understanding of the underlying causes of rheumatic diseases by systematically integrating genetic studies within our translational research team.

You will be tasked with gaining and maintaining a comprehensive understanding of genetic studies in rheumatology and related fields. This involves staying updated through literature surveys, attending conferences, engaging in discussions with team members, and participating in internal lab meetings.

Your responsibilities will include conducting, analyzing, and interpreting genetic analyses for various projects. This will involve developing genetic risk scores to differentiate between diseases or disease subsets, continuing ongoing work within our LUMC-led GWAS consortium focusing on the remission of Rheumatoid arthritis, supporting and guiding the etiological hypothesis of other projects by demonstrating genetic associations with findings, and investigating genetic interactions with phenotypes.

Additionally, you will take a leading role in writing manuscripts based on your analyses and findings. You will have the opportunity to present your results at both national and international scientific meetings, as well as consortium meetings.

Furthermore, you will play a role in co-supervising junior scientists, including data scientists, MSc/BSc students, and PhD students within the team. This position offers a unique opportunity to contribute significantly to the field of rheumatology through cutting-edge genetic research and collaboration within a dynamic research environment.

About you

  • A PhD in genetic epidemiology or a related field, with experience conducting genetic association studies and downstream analyses;
  • Recommended (but not required) experience in areas such as RNAseq, omic analyses, functional genetics, or clinical epidemiology;
  • Strong motivation and dedication to expanding skills within a clinical setting;
  • Understanding of the opportunities and challenges of working in international collaborations under European grants, with fixed deliverables and milestones;
  • Effective project and time management abilities, with a collaborative approach to teamwork;
  • Ambitious and capable of taking responsibility for research projects, while aligning well with colleagues. Organized, independent, proactive, and resilient in the face of setbacks;
  • Excellent analytical, communication, and writing skills, with a clear and concise style;
  • Fluency in English, both written and spoken.

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