Postdoctoral Fellow - Cancer Epigenetics
Postdoctoral Fellow - Cancer Epigenetics
IEO - European Institute of Oncology
Milan, Italy
We are looking for an enthusiastic postdoctoral fellow with strong expertise in molecular and cellular biology to lead a project aimed at identifying epigenetic determinants of acquired resistance to therapy in cancer. The project is part of a EU-funded collaborative study that involves five high-profile partners across Europe. The study will employ SmartCodes, next-generation molecular barcodes developed by our collaborator Greg Hannon in Cambridge UK, which allow prospective isolation and characterization of therapy-resistant cells from treatment naïve tumors. Depending on candidate’s interests, other projects related to the broader research of the lab may also be considered.
Key experience and competencies:
Essential
- PhD in molecular and/or cellular biology, biochemistry, or related;
- Strong expertise in molecular biology (advanced molecular cloning and NGS-based approaches), cell culture(transfection, transduction, clone isolation, medium- or high-throughput cell culturing), basic biochemistry and quantitative microscopy;
- Good knowledge and expertise in chromatin biology;
- Track record of writing papers as evidenced by publications or submitted manuscripts in peer-reviewed journals, with a least one first-author publication;
- Excellent spoken and written English.
Desirable
- Experience with CRISPR technology, including targeted genome editing and NGS-based read-outs;
- Experience with molecular barcoding/lineage tracing;
- Experience with animal work (e.g. transplantation assays and xenograft models).
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