(Senior) Scientist - High Throughput Screening
(Senior) Scientist - High Throughput Screening
Selvita
Krakow, Poland
Key responsibilities
- Assistance in the design and construction of the HTS platform at Selvita
- Developing target-relevant biochemical and cell-based assays including optimization, validation and troubleshooting (screening assay robustness, sensitivity, reproducibility)
- Evaluation of the novel cell-based screening initiatives for implementation into the group portfolio
- Converting assays into HTS format - assay miniaturization to 384-well/1536-well format
- Design and implementation of the key in vitro pharmacology experiments for low-throughput compound profiling (efficacy, selectivity, mechanism of action)
- Performing HT screens and hit identification
- Statistical analysis, reporting and critical data evaluation for providing a scientific contribution to internal drug discovery projects
- Ensuring all tasks and responsibilities are performed according to industry-leading scientific and ethical standards and accurately documented in the lab electronic notebook system
Your background
- MSc in pharmacology, molecular biology, biotechnology or similar discipline with minimum 2 years of experience in a biotech/pharma setting or Ph.D. in relevant biological sciences
- Good knowledge of in vitro pharmacology concepts with a strong focus on at least one of the following areas: intracellular signaling, cancer metabolism, immunology, CNS
- Experience in working with cell lines and cell-based assays in microplate format
- Prior experience with mid-to-high throughput screening, liquid handling devices and lab automation will be a plus
- Analytical and problem-solving skills with proven troubleshooting experience
- Well-developed multi-tasking, flexibility and team working skills
- scientific presentation and interpersonal communication skills
- Fluency in English
Don't forget to mention EuroScienceJobs when applying.
© EuroJobsites 2024
