Postdoctoral Position in Obesity and Diabetes
Postdoctoral Position in Obesity and Diabetes
Institut Cochin
Paris, France
Research project
Investigate a novel regulator in obesity:
Obesity, overweight, and type 2 diabetes (T2D) are major public health concerns. Adipose tissue stores excess energy as fat and acts as an endocrine organ, releasing hormones and inflammatory molecules that influence metabolism, appetite, and insulin sensitivity. Our research focuses specifically on the function of G proteincoupled receptors (GPCRs) involved in obesity/diabetes. GPCRs are of significant therapeutic interest because they can be easily targeted by drugs. We are seeking a motivated and talented Postdoctoral Researcher to join a funded project aimed at uncovering the role of a GPCR in obesity and diabetes, using cellular and in vivo experimentation (PI: Dr. Julie DAM).
Main Activities
- Investigate the mechanisms of action of the novel regulator;
- Characterize obesity mouse model of transgenic mice;
- Main techniques to be performed by the postdoctoral fellow: cell culture (adipocyte primary culture), western blot, RT-qPCR, cell signaling, immunoprecipitation, in vivo metabolic profiling, mitochondrial function analysis, confocal microscopy, histology.
Expertise
- Experience in cellbiology, mammalian cell culture;
- Experience in analysis of gene expression by RT-qPCR, detection of protein by western-blot an dby immunofluorescence;
- Experience in microscopy imaging (confocal);
- Experience in basic mouse experimentation;
- Expertise in primary culture of adipocytes would be appreciated.
Skills
- Good communication skills in English, orally and written;
- Strong organization and scientific rigor skills;
- Curiosity and Motivation for scientific projects;
- Ability to solve problems;
- Team-oriented personality;
- Strong analytical skills and experience with data analysis tools;
- Diploma level PhD in cell biology, biochemistry, physiology or a related field.
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