Senior Scientist - Purification Development

Senior Scientist - Purification Development

Lonza

Slough, United Kingdom

Key responsibilities:

• Plan and design own experiments for development of downstream processes for therapeutic proteins;
• Design and execution of high throughput chromatography methods;
• Responsible for the execution and delivery of own projects with particular attention to safety, quality, on time and right first time;
• Escalate technical issues in a timely fashion;
• Ensure that experimental details, raw data and results are recorded as appropriately;
• Collate, analyse and evaluate data to produce good quality process information;
• Operate as part of a cross-functional project team;
• Prepare and deliver high quality presentations, protocols and reports;
• Ensure own training is up to date;
• Contribute to the efficient running of the laboratories.

Key requirements:

• BSc/PhD in Biotechnology or in a relevant scientific discipline and appropriate laboratory experience;
• Tecan Evo and/or Tecan Fluent programming experience;
• Theoretical knowledge of protein chemistry and protein purification;
• Strong practical laboratory skills;
• Practical experience with laboratory scale AKTA chromatography;
• Strong written and verbal communication skills;
• Strong planning and organisational skills;
• IT proficient (i.e. Microsoft Office);
• Proficient in the use of Unicorn software.

Desirable:

• Knowledge of GLP/GMP;
• Experience of process transfer and scale up to cGMP manufacture;
• Experience of managing external stakeholders;
• Knowledge of GAP analysis methodologies (e.g. FMEA, Cause and effect analysis);
• Experience of process characterisation/validation;
• Operational excellence (5S or similar) experience.

Qualities and Attitude:

• Excellent attention to detail;
• Must have excellent interpersonal skills to work effectively as part of a multidisciplinary/project team;
• Prioritise and manage own time effectively;
• Show initiative for problem solving and generating new ideas;
• Work independently to an agreed plan;
• Able to work with minimal supervision;
• Comfortable working in a fast paced environment with changing priorities;
• Willingness to support other activities within the department.

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