The overarching goal of the lab is to combine molecular cell biology, microbiology, various microscopy techniques, ex vivo and animal models to decipher the molecular and cellular events leading to vascular dysfunction, thrombosis, organ failure and death during infection by Neisseria meningitidis.
The candidate will play a central role in our programme of work studying the molecular and metabolic mechanisms that control bacterial virulence and the evolution of the infection towards a lethal sepsis.
In particular, the candidate will characterize the biological functions and mode of action of novel bacterial virulence factors we recently identified.
The candidate will join a friendly group of cellular microbiologists working at the Institut Cochin. He/she will help with training the lab’s graduate students and collaborate in other laboratory activities. He/she will benefit from an excellent training and stimulating environment for research located in the heart of Paris, our cutting-edge science facilities, and from existing external collaborations within France and internationally.