Bioengineer in Microphysiological Systems
Bioengineer in Microphysiological Systems
EPFL - Swiss Federal Institute of Technology Lausanne
Lausanne, Switzerland
Your mission
The EPFL Bioengineering & Organoids Technology platform (BET platform) at the AGORA Cancer Research Center Lausanne, welcomes applications for a position of Bioengineer.
We are currently seeking an accomplished specialist in Microphysiological Systems to join our dynamic team. Your role will encompass active participation in the BET platform's operations, encompassing both services and R&D endeavors to support the users of the BET platform from AGORA and beyond.
The selected candidate will play a pivotal role in advancing the deployment and implementation of services in the area of advanced multicellular models, including organoids, 3D imaging, precision liquid handling. The primary objective is to provide support and expertise to facilitate the research endeavor of local researchers.
Your responsibilities will span a wide range of tasks, encompassing the establishment of imaging and automation pipelines, the training and education of the BET users on the usage of our instruments, infrastructure and technologies, the support of the BET users in the design, fabrication, and deployment of microphysiological systems and assays, including systems requiring biomaterials, precision liquid handling and microfluidics.
Your contributions will also extend to fostering the growth of in-house proficiency within the BET team, actively participating in collaborative research initiatives with researchers across the AGORA Cancer Research Center and its partner institutions.
This role presents a unique opportunity to channel your expertise into impactful projects and collaborations, within a dynamic academic, interdisciplinary and translational ecosystem. Join us in driving innovation at the forefront of bioengineering for cancer research by submitting your application.
Main duties and responsibilities include
- Provide expertise, training and support to the users of the BET platform in the design, implementation and use of instruments, processes and experimental setups. Train the users towards independent use of selected instruments and processes;
- Gain advanced hands-on expertise on the operation of high-end pieces of equipment (e.g. robotized high-content confocal microscope, precision liquid handling automation systems, 3D printers, microfluidics) operated by the platform to support the BET users;
- Carry out the necessary technical and R&D work for the execution of services and collaboration projects, for the implementation of existing and for the development of novel assays and technologies, in compliance with good laboratory practices and internal procedures;
- Assist the BET platform director in developing novel technologies and services in the area of microphysiological systems, including biomaterials; with the design of experiments; and with the preparation of collaboration research proposal and the supervision of projects;
- Assume shared responsibility for organizing and implementing routine lab schedules and procedures;
- Participate to the overall development of the BET platform activities, including infrastructure development, communication efforts, IT best-practice effort, team building, etc.;
- Participate in the management, maintenance and calibration of the instrument park, ordering and monitoring consumable stocks, reagent and inventory, etc., in collaboration with your colleagues.
Your profile
- You have received education and acquired advanced expertise in Bioengineering, Life Science Engineering, Microengineering or equivalent discipline, with a strong interest in cancer biology, immunology and human in vitro models;
- You have solid experience in working with cell culture and advance 3D cellular models;
- You have experience with at least some of the following: precision liquid handling, microphysiological systems, biomaterials, microfluidics and rapid prototyping;
- You have solids skills in confocal microscopy, image analysis, as well as in programming computational pipelines, possibly even with machine/deep learning approaches;
- You can rapidly help implement and troubleshoot systems and experiments;
- You understand the modus operandi of a scientific platform and you are keen to contribute in supporting the research effort of collaborators and users of the platform;
- You are a good listener and you are quick to understand the aims and technicalities of a project and to identify solutions and potential pitfalls;
- You can handle multiple projects in parallel and adjust to changing priorities with the help of your supervisor;
- You can apply design principles and understand the difference between a proof-of-concept and a functional prototype;
- You are methodological in your work, have a good sense of organisation and demonstrate a good ability to report about your progress to your manager and collaborators;
- You demonstrate an ability to learn and perform diverse tasks independently, and are able to seek help when needed;
- You have an interest in expanding your knowledge and expertise, as well as in potentially developing new cutting-edge methods and technologies;
- You are trustworthy, committed and diligent;
- You demonstrate a good team spirit and you like to collaborate in an interdisciplinary environment;
- Good command of English required, good knowledge of French appreciated;
- Good mastery of IT tools and advanced knowledge of specialized scientific software and programming languages (e.g. LabView, Matlab, C/C++, Python,...).
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