Lead Scientist
Lead Scientist
Lonza
Cambridge, United Kingdom
The role:
Are you passionate about pushing the boundaries of biotechnology? Do you thrive in a cutting-edge environment where your work directly impacts the future of medicine? If so, Lonza Cambridge is looking for you!
We are on the hunt for a visionary Cell Line Development Lead Scientist who can bring their expertise and creativity to our dynamic team focused on developing next-generation, industrially relevant cell expression platforms. Join us in revolutionising the development of therapeutic proteins and biologics at the forefront of innovation.
Key responsibilities:
- Contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins.
- Explore innovative ideas to optimise the cell line development (CLD) process including the use of state-of-the-art automation equipment, novel technologies, and more, to push the limits of what’s possible.
- Independently lead several collections of projects from design and execution of experiments to data analysis and presenting of findings with confidence and clarity.
- Work closely with cross-functional groups within & outside of R&D to deliver solutions or improvements in recombinant protein expression and support commercialisation.
- Actively keep abreast of relevant academic literature (e.g., in the field of cell engineering and expression technologies), applying them in creative ways.
Key requirements:
- PhD degree/Postdoctoral fellow with at relevant experience in an R&D setting Or BSc/Masters with relevant experience.
- Proven experience in mammalian cell line development and implementation/development of automation for cell line screening and optimisation, ideally within a high-stakes industrial environment.
- Proficiency in CHO cell culture, stable transfection, single cell isolation (i.e. Beacon™ Opto-fluidic Technology), clonal expansion, and small-scale bioreactors (i.e. Ambr15).
- Ability to translate basic scientific concepts into practical applications and integrate scientific knowledge to solve problems and issues. Communicate and apply scientific ideas effectively
- Establishes and maintains good working relationships with key project team-level stakeholders. Proactive in building relationships within the group, forthcoming with support, and demonstrates strong ownership of deliverables.
- Thrives in a collaborative environment and can also drive projects forward independently while supervising other junior members in the team.
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