Associate Scientist Bioreactor Process Design
Associate Scientist Bioreactor Process Design
Evotec
Toulouse, France
General Summary:
Just-Evotec Biologics is looking for Associate Scientist of Bioreactor Process Design to join a fast-paced, collaborative, and multidisciplinary team working on upstream process development (perfusion and intensified fed-batch) projects. In this role, you will participate in further developing and refining Just’s next-generation continuous bioprocessing platform, which we are currently running in our Seattle and Redmond manufacturing facilities at 500L and 1000L scale. Just-Evotec employees are driven by our mission: to expand access to therapeutics by substantially driving down the cost of goods through process technology development. This role is well-positioned to have a substantial impact on patients and the biotechnology industry.
This position will be part of a team to perform upstream process development for early and late-stage processes and will include process development, optimisation, characterization, and technology transfer for intensified, continuous processes. The successful candidate will be detail-oriented, self-motivated, efficient, curious, and work well in a team environment. Strong written and verbal communication skills, including the ability to communicate effectively over teleconferences and web-based meetings, are necessary.
Missions and responsibilities:
- Assisting in all Lab activities including experiment execution, Bioreactor assembly, Autoclave, Media/buffer preparation, Bioreactor sampling and daily sample analysis, Sample storage etc.
- Executing statistically designed experiments (DOE) with support from Scientist/Senior Scientists.
- Responsible for bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance.
- Responsible for equipment calibrations and Media preparations in the Lab.
- Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.
- Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.
- Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions.
- Carry out Development/Characterisation/optimisation experiments, accurately document results, and produce experimental reports.
- Responsible for own professional attitude and for sharing knowledge for the benefit of others or on demand.
- Author, amend and review operating documents, such as WI, SOPs, guidelines, and data records. Willing to take on additional activities.
- Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.
- Working with vendors and manufacturers.
- Potential for weekend work (5-day work week/2 consecutive days off).
Knowledge, skills and abilities:
- Excellent attention to detail, focused when completing technical tasks.
- Strong writing skills and efficient at documentation.
- Able to stay organized in complex situations, keep track of multiple tasks and data.
- Enthusiastic problem-solver.
- Experience with Microsoft Office apps (Word, PowerPoint, Excel).
- Experience with cell culture operations, filtration techniques, automation, analyzing data using statistical tools.
Experience and education:
- Bachelor degree in Engineering, Biochemistry or related field and +2 years of relevant experience.
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