Postdoc Metabolomics Group

Postdoc Metabolomics Group

Leiden University Medical Center

Leiden, Netherlands

Join the dynamic team at LUMC as a Postdoc, where you will develop cutting-edge LC-MS/MS methods for identifying and quantifying endogenous metabolites. This unique role not only allows you to contribute to groundbreaking research but also immerses you in a collaborative environment with Boehringer Ingelheim Pharma GmbH &CoKG, enhancing drug discovery projects. Experience the thrill of integrating analytical techniques while working alongside experts in a vibrant research community dedicated to advancing biomedical science.

About your role

In this postdoctoral position, you will be primarily responsible for developing, qualifying, and standardizing an LC-MS/MS method aimed at the robust identification and quantification of a wide range of endogenous metabolites. This method will facilitate the exploration of crucial biochemical pathways. After successful development and qualification, you will transfer the method to our partner’s laboratories at Boehringer Ingelheim in Biberach Pharma GmbH &CoKG, Germany, ensuring its full operational capability and integration within their laboratory environment. Additionally, you will contribute to establishing a comprehensive data processing pipeline for metabolomics results, aligning findings with biochemical pathways and supporting multi-omics approaches through close collaboration with the Boehringer Ingelheim team. Your top-5 tasks are:

  • Develop and qualify an LC-MS/MS method for identifying and quantifying endogenous metabolites.
  • Transfer the developed method to Boehringer Ingelheim Pharma GmbH &CoKG, ensuring operational readiness.
  • Implement a robust data processing pipeline for metabolomics results.
  • Collaborate closely with the Boehringer Ingelheim team to align processes with project goals.
  • Contribute to multi-omics approaches by mapping metabolomics results to biochemical pathways.

This role requires a strong background in analytical chemistry and metabolomics, along with excellent communication skills for effective collaboration. You will be expected to engage in both wet lab work and computational analysis, making it essential to have experience in data processing techniques relevant to metabolomics.

About you

You are a team player who communicates effectively and conveys complex ideas clearly. With a strong command of the English language, you are capable of engaging in constructive discussions and collaborating within a multidisciplinary environment. You possess a strong eagerness to learn and think outside the box, enabling you to propose innovative solutions to research challenges. Furthermore, you have:

  • A PhD in Biochemistry, Metabolomics, or Analytical Chemistry, demonstrating in-depth knowledge and expertise in relevant scientific disciplines.
  • Experience with LC-MS technologies and a solid understanding of the principles and applications of liquid chromatography-mass spectrometry.
  • Foundational coding skills in R, Python, or other relevant tools for data analysis.
  • Experience in the field of metabolomics, which enhances your profile.
  • Adaptability and curiosity, allowing you to be open to new methodologies and easily integrate into diverse research teams.

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